This Webpage is devoted to one of our datasets addressing human macrophage activation and differentiation.
This dataset has been introduced in one of our recent papers:
Network engineering on the transcriptional level reveals a multi-spectrum model of human macrophage activation. Jia Xue, Susanne V. Schmidt, Jil Sander, Astrid Draffehn, Wolfgang Krebs, Inga Quester, Dominic De Nardo, Trupti D. Gohel, Martina Emde, Lisa Schmidleithner, Hariharasudan Ganesan, Andrea Nino-Castro, Michael R. Mallmann, Larisa Labzin, Heidi Theis, Michael Kraut, Marc Beyer, Eicke Latz, Tom C. Freeman, Thomas Ulas, Joachim L. Schultze. Immunity, (2014), http://dx.doi.org/10.1016/j.immuni.2014.01.006
We have compiled the data in different formats for you to download them and use them in your own studies and analysis. If you have questions concerning the data and data formats, please contact us.
We have compiled the scripts and algorithms used and also have summarized all software and tools we applied in our study.
Here we will compile further analyses based on our large human macrophage activation dataset. Please visit us regularly.
The expression of all genes present in the dataset can be nicely visualized via the following link: https://www.stemformatics.org/datasets/search?ds_id=6286#
This work was supported by the German Research Foundation (Sonderforschungsbereich 645, SFB 704, SFB 832, INST 217/575-1, INST 217/576-1, and INST 217/577-1 to J.L.S.). J.L.S. and E.L. are members of the Excellence Cluster ImmunoSensation. The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme FP7/2077-2013 under REA grant agreement no. 317445.