German Center for Neurodegenerative Diseases (DZNE)
+49 (0) 228 / 43302-390 (Office)
+49 (0) 228 / 43302-688 (Secretary)
Our group is interested in the differentiation and the plasticity of neuronal dendrites. Dendrites represent the input compartment of neurons: they collect information through specific connections that they build with suitable neuronal partners within the nervous system. Thus, the formation of appropriate dendritic arbors is essential for the generation of functional connections within the nervous system and for correct processing of information. Indeed, several human syndromes that lead to mental retardation are accompanied by defective dendrite organization in the central nervous system. Importantly, dendrites remain plastic during adult life and rearrangements of dendrite subdomains accompany plastic process, including adaptation to a changing sensory environment and potentially the formation of long-term memories.