Working with us means joining a research institute within the University of Bonn that is dedicated to the promotion of talented young researchers. It means the opportunity to conduct cutting-edge research in a multidisciplinary, resource-rich environment where people come together to collaborate, share ideas and inspire each other's research aspirations.
1 PhD student position (m/f/d)
The group of Prof. Günter Mayer offers one PhD student position available from the earliest possible date for 3 years (TV-L E13, 50 %). We are searching for a highly motivated and qualified scientist with research interests in the area of:
Targeting of dendritic cells (DCs) became of utmost importance in immunotherapy. Upon recognition of antigenic structures, DCs deliver all signals necessary for an adequate activation of the effectors of the adaptive immune system, the T cells. Selective and efficient targeting requires eligible carrier molecules and one promising class are aptamers. Briefly, aptamers are single-stranded oligonucleotides that specifically bind target molecules by adopting unique conformations. We identified DC-binding aptamers and demonstrated their applicability as selective and efficient DC-targeting carriers. They bind to DCs, are internalized and localized within appropriate antigen processing compartments and, most importantly, are potent mediators of targeted activation of specific T cells. The new candidate will further investigate and improve the efficiency of the aptamers for cancer immunotherapeutic approaches.
The requirements for the ideal candidate are
- a strong interest in immunology, cell biology and molecular biology
- strong experiences in immunological assays (e.g. T cell proliferation/cytotoxicity assays), cell culture techniques (e.g. cultivation of primary cells and cell lines, flow cytometry) and handling nucleic acids and peptides (e.g. PCR, gel electrophoresis, sequencing)
- experiences with aptamers, mouse models and confocal microscopy are advantageous
- basic knowledge in HPLC, mass spectrometry
- willingness to learn and develop new techniques and skills
Applicants require a diploma/master degree in a Life Science discipline (Immunology, Biology, Biochemistry, other related disciplines), an excellent command of English and the ability to work in a team. We encourage interested candidates to apply immediately for the open positions by submitting their credentials, CV and motivation letter to
Position vacancies for non-academic staff will be advertised on this page and that of the University of Bonn.
For people interested in studying with us, please visit our Education and Training page for more details on study courses and application information.
People holding fellowships at any career level, are strongly encouraged to apply directly to the lab head of a specific research group of interest at any time. Information regarding German Research Funding opportunities can be found below.
International staff and students are also encouraged to visit our International LIMES page for more helpful links and information about life at the LIMES institute.
There are many funding streams supporting scientists transitioning from different labs, countries and career levels. Ranging from organizations such as the German Academic Exchange Service (DAAD), EMBO, and foundations such as the Alexander von Humboldt Foundation, to programs including the Human Frontiers Science Program, you will find something suitable for you.
To help kick-start start your research, the Research in Germany website provides comprehensive information about the German research funding system, funding organizations and funding programs for international researchers at all career levels.
The city of Bonn, on the river Rhine with a population of 320,000 is a vibrant, multicultural university town and ideal location for our institute. The university district is dominated by the ‘Bonner’ youth and numerous cafés, restaurants and bars add to the lively atmosphere in the inner city. Bonn is the birthplace of Ludwig van Beethoven, who lived here for over 20 years before his life took him to Vienna. It is a cultural center that hosts prestigious concerts and exhibitions, attracting over 1 million visitors from around the world to its Museum Mile each year.
The city is also home to 18 United Nations organizations and several world-class research and education institutions. The international University of Bonn (German: Rheinische Friedrich-Wilhelms-Universität Bonn) was founded in its present form in 1818, by King Frederick William III of Prussia and is now one of Germany's most reputable institutions of higher learning with over 30,000 students. Among its most famous alumni are seven Nobel Prize winners, fourteen laureates of the Gottfried Wilhelm Leibniz Prize, two winners of the Fields Medal, Pope Benedict XVI, Heinrich Heine, Karl Marx, Konrad Adenauer, Joseph Schumpeter and Friedrich Nietzsche. It is also one of the German universities, which was included as part of the Excellence Initiative in the funding lines the Cluster of Excellence and Graduate Schools.