Working with us

Working with us means joining a research institute within the University of Bonn that is dedicated to the promotion of talented young researchers. It means the opportunity to conduct cutting-edge research in a multidisciplinary, resource-rich environment where people come together to collaborate, share ideas and inspire each other's research aspirations. 

Current job vacancies

The Kolanus lab at the Life & Medical Sciences Institute (Molecular Immune- and Cell Biology), University of Bonn, has an opening for a 

PhD student position (65%) 

The highly qualified candidate will work on the molecular mechanisms of chemokine gradient sensing of immune cells. 

Gradients of chemoattractants guide the recruitment of immune cells into organs, but it is incompletely understood how cells sense and respond to such stimuli. In recent years, we have engaged in setting up high-end microscopy- and microfluidics-based techniques to visualize and analyze migratory cell behavior quantitatively (Quast et al., Front Cell Dev Biol., 2022). The research project is designed to investigate cytoskeletal dynamics and intracellular events during navigation and turning behavior of motile immune cells. In the course of this, we will also use a CRISPR mutagenesis screen with direct in situ identification of functional hits. 

This project is embedded in the DFG-funded International Research Training Group (IRTG 2168) between the Rheinische-Friedrich-Wilhelms-University of Bonn/Germany and the University of Melbourne/Australia. The Bonn & Melbourne Research and Graduate School (Bo&MeRanG) focuses on the role of myeloid immune cells and adaptive immunity in the context of infection and inflammation. Students will perform the core of their 3-years PhD project in Bonn and will spend 1 year in Melbourne, jointly supervised by internationally leading principal investigators from both universities. Successful completion results in a joint PhD, which is jointly awarded by the University of Bonn and the University of Melbourne. 

The ideal candidate will be highly motivated and team-oriented with a strong interest in cell biology, microscopy, cell migration and immunology, a first-class academic degree in a life science-related discipline (Master`s degree in biology, molecular biology or biochemistry or equivalent), a strong background in cell biology or biochemistry and enthusiasm for working in the highly-competitive field of molecular cell biology. Candidates should have strong communicative skills (fluent spoken and written English). 

We offer: 

  • The salary will be according to the German salary scale TV-L (EG 13) 
  • A “Jobticket” (subsidized public transport) is available 
  • There is also possibility to use the day care center 
  • Supplementary benefits in the public sector (pension plan according to VBL) 

The University of Bonn is committed to diversity and equal opportunity. It is certified as a family-friendly university. It aims to increase the proportion of women in areas where women are under-represented ant to promote their careers in particular. It therefore urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable individuals with a certified serious disability and those of equal status are particularly welcome. 

Applicants should send their application documents in a single pdf file (max. 5 MB) including motivation letter, CV, scanned academic degrees, list of publications and the contact details of two references. Successful candidates will begin on January 1, 2023 or later. 

Please send your application by email until November 21, 2022 to 

Prof. Dr. Waldemar Kolanus
kolanus.sekretariat@uni-bonn.de 
Life & Medical Sciences (LIMES) Institute 
University of Bonn 
Carl-Troll-Straße 31 
53115 Bonn, Germany 

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The University of Bonn belongs to Germany’s most recognized institutions for research and higher education and was awarded the status of a University of Excellence in 2019. 

The group of Prof. Günter Mayer at the LIMES Institute, Center of Aptamer Research & Development, Chemical Biology Unit, offers a PhD student position (TV-L E13, 50 %) available from the earliest possible date for 3 years. We are searching for a highly motivated and qualified scientist with research interests in the area of:

Gene Therapy & Systems Aptanomics

Scientific background
Perturbations causing diseases are in most cases signaling pathway related, e.g. Ras signaling, MAP kinase signaling, mTOR, inflammasome, etc. These pathways consist of tens to hundreds of individual proteins, each of which potentially being a drug target. However, drugability of each component is difficult to assess. Aptamers are widely used in therapeutic or diagnostic
approaches and as being RNA molecules, they can be expressed intracellularly and thus qualify for gene therapy approaches.
The goal of this project is the automated and systematic development of RNA aptamer libraries binding to a variety of pathway components and their subsequent cellular expression. Cellular aptamer binding effects will be screened, e.g. by flow cytometry, live/dead selection, induced/inhibited migration, adhesion etc., for aptamers effectively perturbing signaling events in mammalian cells like cancer cells, immune cells or neurons. RNA aptamer sequences will be identified using barcoding and NGS analysis. The results of this study will elucidate how perturbations in signaling pathways contribute to diseases and open paths for gene therapy approaches. The latter will allow the rapid translation of aptamers into animal model systems (mice), for example using AAV based expression systems.

The requirements for the candidates are

  • high intrinsic motivation and interest in science and research
  • strong interest in molecular biology, chemical biology and cell biology
  • experiences in molecular biology methods (e.g. PCR, in vitro transcription, sequencing) and cell culture techniques (e.g. cultivation and transfection of cell lines, flow cytometry, confocal microscopy)
  • high motivation to learn and develop new techniques and skills (including soft skills)
  • willingness to conduct animal experiments at a later stage of the project, although this is not a requirement.

Applicants require a diploma/master degree in a Life Science discipline (Biology, Biochemistry or other related disciplines), an excellent command of English and the ability to work in a team. We encourage interested candidates to apply immediately for the open position by submitting their credentials, CV and motivation letter to gmayer@uni-bonn.de and silvana.hassel@uni-bonn.de.

The LIMES Institute is an interdisciplinary institute, covering immunosciences, membrane and lipid biochemistry as well as (neuro)physiology. Besides these topics the Chemical Biology unit is focussed on nucleic acid (bio)chemistry and prediction of protein assemblies. The Transdisciplinary Research Area ‘Life &Health’, in which most if the members of the LIMES Institute are embedded, provides a greater framework of interdisciplinary research and access to core facilities scattered around the life sciences campuses of the University, enabling multifaceted research opportunities, collaborative initiatives and optional support of translational and transfer endeavours.


Information for non-academic staff:

Position vacancies for non-academic staff will be advertised on this page and that of the University of Bonn.

Opportunities for Academic Staff and Students

For people interested in studying with us, please visit our Education and Training page for more details on study courses and application information.  

People holding fellowships at any career level, are strongly encouraged to apply directly to the lab head of a specific research group of interest at any time. Information regarding German Research Funding opportunities can be found below.

International staff and students are also encouraged to visit our International LIMES page for more helpful links and information about life at the LIMES institute.

Funding and Support

There are many funding streams supporting scientists transitioning from different labs, countries and career levels. Ranging from organizations such as the German Academic Exchange Service (DAAD), EMBO, and foundations such as the Alexander von Humboldt Foundation, to programs including the Human Frontiers Science Program, you will find something suitable for you. 

To help kick-start start your research, the Research in Germany website provides comprehensive information about the German research funding system, funding organizations and funding programs for international researchers at all career levels. 

Tip: Funding databases offered by the German Academic Exchange Service (DAAD), and EURAXESS are a great tool to help dissect relevant fellowship opportunities. 

In addition, the Human Resource Development team at the University of Bonn offers both researchers and technical and administrative staff members a wide range of consultation offers and seminars.


Living and working in Bonn

The city of Bonn, on the river Rhine with a population of 327,000 is a vibrant, multicultural university town and ideal location for our institute. The university district is dominated by the ‘Bonner’ youth and numerous cafés, restaurants and bars add to the lively atmosphere in the inner city. Bonn is the birthplace of Ludwig van Beethoven, who lived here for over 20 years before his life took him to Vienna. It is a cultural center that hosts prestigious concerts and exhibitions, attracting over 1 million visitors from around the world to its Museum Mile each year.

The city is also home to 18 United Nations organizations and several world-class research and education institutions. The international University of Bonn (German: Rheinische Friedrich-Wilhelms-Universität Bonn) was founded in its present form in 1818, by King Frederick William III of Prussia and is now one of Germany's most reputable institutions of higher learning with over 34,000 students. Among its most famous alumni are seven Nobel Prize winners, fourteen laureates of the Gottfried Wilhelm Leibniz Prize, two winners of the Fields Medal, Pope Benedict XVI, Heinrich Heine, Karl Marx, Konrad Adenauer, Joseph Schumpeter and Friedrich Nietzsche. It is also one of the German universities, which was included as part of the Excellence Initiative in the funding lines the Cluster of Excellence and Graduate Schools.