Using Systems Biology to delineate the role of mononuclear phagocytes during health and disease.
Mononuclear phagocytes, such as Dendritic cells, macrophages and monocytes are gatekeepers of organ homeostasis and inflammation.
In the Schlitzer Lab we study how these cells develop and gain their specialized functions during health and disease.
To gain novel insights into this spectacular cellular compartment of the innate immune system we utilize state of the art high dimensional transcriptomic, spatial and proteomic approaches coupled to computational analysis.
This integrative approach allows us a unique perspective on the complexity of the human and mouse mononuclear phagocyte system.