Publikationen unter Beteiligung von LIMES-Studenten

Ab 2007 sind in wissenschaftlichen Publikationen, deren zugrunde liegenden Experimente an der Universität Bonn durchgeführt wurden, 197 Autorenschaften von Studierenden oder Absolventen der Molekularen Biomedizin oder des Life and Medical Sciences in der Datenbank für biomedizinische Publikationen Pubmed aufgelistet (Stand August 2012). Aus den Masterjahrgängen 10/11 und 11/12 werden bereits zum jetzigen Zeitpunkt sieben Autorenschaften in Pubmed geführt (Stand August 2012). 

Die 20 wichtigsten Publikationen mit Beteiligung von LIMES-Studenten der letzten Jahre

Gotot J, Gottschalk C, Leopold S, Knolle PA, Yagita H, Kurts C, Ludwig-Portugall I. (2012) Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo. Proc Natl Acad Sci U S A.  109(26):10468-73. 

Janzer A, Stamm K, Becker A, Zimmer A, Buettner R, Kirfel J. (2012) The H3K4me3 histone demethylase Fbxl10 is a regulator of chemokine expression, cellular morphology and the metabolome of fibroblasts. J Biol Chem. 287(37):30984-92.

Ladewig J, Mertens J, Kesavan J, Doerr J, Poppe D, Glaue F, Herms S, Wernet P, Kögler G, Müller FJ, Koch P, Brüstle O. (2012) Small molecules enable highly efficient neuronal conversion of human fibroblasts. Nat Methods. 9(6):575-8.

Ludwig KU, Mangold E, Herms S, Nowak S, Reutter H, Paul A, Becker J, Herberz R, Alchawa T, Nasser E, Böhmer AC, Mattheisen M, Alblas MA, Barth S, Kluck N, Lauster C, Braumann B, Reich RH, Hemprich A, Pötzsch S, Blaumeiser B, Daratsianos N, Kreusch T, Murray JC, Marazita ML, Ruczinski I, Scott AF, Beaty TH, Kramer FJ, Wienker TF, Steegers-Theunissen RP, Rubini M, Mossey PA, Hoffmann P, Lange C, Cichon S, Propping P, Knapp M, Nöthen MM. (2012) Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. Nat Genet. 44(9):968-71 

Tittel AP, Heuser C, Ohliger C, Llanto C, Yona S, Hämmerling GJ, Engel DR, Garbi N, Kurts C. (2012) Functionally relevant neutrophilia in CD11c diphtheria toxin receptor transgenic mice. Nat Methods. 9(4):385-90.

Zehner M, Chasan AI, Schuette V, Embgenbroich M, Quast T, Kolanus W, Burgdorf S. (2011) Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation. Proc Natl Acad Sci U S A.  108(24):9933-8.

Pelka K, Latz E. (2011) Getting closer to the dirty little secret. Immunity. 34(4):455-8.

Schildberg FA, Wojtalla A, Siegmund SV, Endl E, Diehl L, Abdullah Z, Kurts C, Knolle PA. (2011) Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism. Hepatology. 54(1):262-72.

Hochheiser K, Engel DR, Hammerich L, Heymann F, Knolle PA, Panzer U, Kurts C. (2011) Kidney Dendritic Cells Become Pathogenic during Crescentic Glomerulonephritis with Proteinuria. J Am Soc Nephrol. 22(2):306-16.

Beyer M, Thabet Y, Müller RU, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Schönfeld EA, Böttcher J, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, Endl E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Mayer G, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, Schultze JL. (2011) Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol. 12(9):898-907.

Koch P, Breuer P, Peitz M, Jungverdorben J, Kesavan J, Poppe D, Doerr J, Ladewig J, Mertens J, Tüting T, Hoffmann P, Klockgether T, Evert BO, Wüllner U, Brüstle O. (2011) Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease. Nature. 480(7378):543-6.

Vinkenborg JL, Karnowski N, Famulok M. (2011) Aptamers for allosteric regulation. Nat Chem Biol. 7(8):519-27.

Bill A, Schmitz A, Albertoni B, Song JN, Heukamp LC, Walrafen D, Thorwirth F, Verveer PJ, Zimmer S, Meffert L, Schreiber A, Chatterjee S, Thomas RK, Ullrich RT, Lang T, Famulok M. (2010) Cytohesins are cytoplasmic ErbB receptor activators. Cell. 143(2):201-11.

Lünse CE, Michlewski G, Hopp CS, Rentmeister A, Cáceres JF, Famulok M, Mayer G. (2010) An aptamer targeting the apical-loop domain modulates pri-miRNA processing. Angew Chem Int Ed Engl. 49(27):4674-7.

Becker T, Loch G, Beyer M, Zinke I, Aschenbrenner AC, Carrera P, Inhester T, Schultze JL, Hoch M. (2010) FOXO-dependent regulation of innate immune homeostasis. Nature. 463(7279):369-73.

Burgdorf S, Schuette V, Semmling V, Hochheiser K, Lukacs-Kornek V, Knolle PA, Kurts C. (2010) Steady-state cross-presentation of OVA is mannose receptor-dependent but inhibitable by collagen fragments. Proc Natl Acad Sci U S A. 107(13):E48-9.

Hofmann A, Wenzel D, Becher UM, Freitag DF, Klein AM, Eberbeck D, Schulte M, Zimmermann K, Bergemann C, Gleich B, Roell W, Weyh T, Trahms L, Nickenig G, Fleischmann BK, Pfeifer A. (2009) Combined targeting of lentiviral vectors and positioning of transduced cells by magnetic nanoparticles. Proc Natl Acad Sci U S A. 106(1):44-9.

Heymann F, Meyer-Schwesinger C, Hamilton-Williams EE, Hammerich L, Panzer U, Kaden S, Quaggin SE, Floege J, Gröne HJ, Kurts C. (2009) Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury. J Clin Invest. 119(5):1286-97.

Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, Morskaya SS, Kirschnek S, Gaffal E, Landsberg J, Hellmuth J, Schmidt A, Anz D, Bscheider M, Schwerd T, Berking C, Bourquin C, Kalinke U, Kremmer E, Kato H, Akira S, Meyers R, Häcker G, Neuenhahn M, Busch D, Ruland J, Rothenfusser S, Prinz M, Hornung V, Endres S, Tüting T, Hartmann G. (2008) 5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma. Nat Med. 14(11):1256-63.

Burgdorf S, Kautz A, Böhnert V, Knolle PA, Kurts C. (2007) Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation. Science. 316(5824):612-6.