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The Rheinische Friedrich-Wilhelms-Universität Bonn is an international research university with a broad spectrum of disciplines. 200 years of history, around 38,000 students, more than 6,000 employees and an excellent reputation at home and abroad: The University of Bonn is one of the most important universities in Germany and has been awarded the title of Excellence University.


The LIMES institute / Dept. Genomics and Immunoregulation is offering a PhD student position (65%) for an initial period of three years with a possibility of extension.


The Life & Medical Sciences (LIMES) Institute is an interdisciplinary institute for basic biomedical research, with a scientific focus on the regulation of lipid metabolism and the immune system in health and disease.
Job description
The project is part of the newly established collaborative research center (CRC) 1454 “Metaflammation and Cellular Programming” and revolves around the impact of lifestyle and environmental influences on the human immune system, which the successful applicant will address experimentally using single-cell omics techniques.
Qualification profile
The PhD student will develop skills in single-cell omics techniques and methods with an immunological focus.
Your duties

  • Planning, and conducting advanced research experiments with an immunological focus,
  • Evaluation and data analysis,
  • Establishment of new research protocols and procedures,
  • Summary of research findings and contribution to publish results in research journals,
  • Responsibility for shared common laboratory operations.

Your profile:

  • Master or equivalent in immunology, biomedicine, or comparable topics,
  • Strong research background in immunology, metabolism and transcriptomics,
  • Practical experience in multi-color flow cytometry, molecular and cell biology, and transcriptomics,
  • Enthusiasm to work in a thriving academic research environment,
  • Ability to work independently as well as in a team at the interface between life sciences and informatics,
  • Very good communications and writing skills in English,
  • An interest to work in an international environment.

We offer:

  • A challenging research project,
  • State of the art technologies to tackle important scientific and medical questions,
  • A thriving interdisciplinary research environment at the LIMES Institute,
  • Fully established bioinformatics department,
  • Memory-Driven Computing hardware resources,
  • A diverse and demanding job with one of the largest employers in the region,
  • Supportive mentoring,
  • Participation in the university-wide pension system (VBL),
  • Numerous offers of university sports,
  • Very good transport connections or the possibility to purchase a VRS major customer ticket or to use inexpensive parking facilities,
  • A possibility to use the day care center,
  • Salary according to salary group 13 TV-L.

The University of Bonn is committed to diversity and equal opportunities. It is certified as a family-friendly university. Its aim is to increase the proportion of women in areas where women are under-represented and to particularly promote their careers. It therefore urges women with relevant qualifications to apply. Applications are treated in accordance with the Land Equality Act. The application of suitable people with proven severe disabilities and persons of equivalent status is particularly welcome.
If you are interested in this position, please submit your application as a single pdf file including a CV, a brief statement of research experiences and interests, a list of publications (if applicable), and the contact details of two referees, to Dr. Anna Aschenbrenner and Prof. Dr. Joachim Schultze office.immunogenomics@uni-bonn.de with the application code 11.21.331 by April 30, 2021. We are looking to fill this position as soon as possible.

 


 

The Rheinische Friedrich-Wilhelms-Universität Bonn is an international research university with a broad spectrum of disciplines. 200 years of history, around 38,000 students, more than 6,000 employees and an excellent reputation at home and abroad: The University of Bonn is one of the most important universities in Germany and has been awarded the title of Excellence University.


The LIMES institute / Dept. Genomics and Immunoregulation is offering a PhD student position (65%) in bioinformatics for an initial period of three years with a possibility of extension.


The Life & Medical Sciences (LIMES) Institute is an interdisciplinary institute for basic biomedical research, with a scientific focus on the regulation of lipid metabolism and the immune system in health and disease.
Job description
The project is part of the newly established collaborative research center (CRC) 1454 “Metaflammation and Cellular Programming” and revolves around the impact of lifestyle and environmental influences on the human immune system, which the successful applicant will address computationally using single-cell omics data improving/developing computational approaches using state-of-the-art tools and IT infrastructure.
Qualification profile
The PhD student will develop skills in bioinformatics data evaluation and analysis, incl. single-cell omics data.
Your duties

  • Planning of single cell experiments,
  • Evaluation and data analysis,
  • Application, improvement and development of computational approaches,
  • Summary of research findings and contribution to publish results in research journals,
  • Responsibility for shared computational operations.

Your profile:

  • Master or equivalent in bioinformatics, computer science or a related field,
  • Strong background in computational biology, bioinformatics, biostatistics,
  • Experience in the analysis of Next-Generation Sequencing transcriptome data, e.g. single-cell RNA-seq and bulk RNA-seq,
  • Strong background in biology, preferably immunology is of advantage,
  • Enthusiasm to work in a thriving academic research environment,
  • Ability to work independently as well as in a team at the interface between life sciences and informatics,
  • Very good communications and writing skills in English,
  • An interest to work in an international environment.

We offer:

  • A challenging research project,
  • State of the art technologies to tackle important scientific and medical questions,
  • A thriving interdisciplinary research environment at the LIMES Institute,
  • Fully established bioinformatics department,
  • Memory-Driven Computing hardware resources,
  • Supportive mentoring,
  • Participation in the university-wide pension system (VBL),
  • Access to extensive university sports program,
  • A diverse and demanding job with one of the largest employers in the region,
  • Very good transport connections or the possibility to purchase a VRS major customer ticket or to use inexpensive parking facilities,
  • A possibility to use the day care center,
  • Salary according to salary group 13 TV-L.

The University of Bonn is committed to diversity and equal opportunities. It is certified as a family-friendly university. Its aim is to increase the proportion of women in areas where women are under-represented and to particularly promote their careers. It therefore urges women with relevant qualifications to apply. Applications are treated in accordance with the Land Equality Act. The application of suitable people with proven severe disabilities and persons of equivalent status is particularly welcome.
If you are interested in this position, please send your application documents including a CV, a brief statement of research experiences and interests, a list of publications (if applicable), and the contact details of two referees to Dr. Anna Aschenbrenner and Prof. Dr. Joachim Schultze office.immunogenomics@uni-bonn.de with the application code 10.21.331 by 30.04.2021. We are looking to fill this position as soon as possible.

 



The bioinformatics unit of the Platform for Single Cell Genomics and Epigenomics (PRECISE) at the Department of Genomics & Immunoregulation at the Life & Medical Sciences (LIMES) Institute of the University of Bonn and the research area Systems Medicine at the DZNE in Bonn are looking for an


Experienced Postdoc in Bioinformatics or Computer Science (100%)


for an initial period of three years with a possibility of extension.

The Rheinische Friedrich-Wilhelms-Universität Bonn is an international research university with a broad spectrum of disciplines. 200 years of history, around 38,000 students, more than 6,000 employees and an excellent reputation at home and abroad: The University of Bonn is one of the most important universities in Germany and has been awarded the title of Excellence University.
The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at the DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine.
PRECISE uses mainly single cell high throughput technologies including next generation sequencing (NGS), to answer basic and translational scientific questions in the area of neurodegenerative diseases and immunology together with local, national and international collaboration partners. PRECISE, in collaboration with industrial partners, offers access to novel, cutting-edge modular compute architectures focusing on memory centric approaches.
 

Your duties


The successful candidate will work at the intersection of life and computer sciences to enable novel analyses of next generation sequencing data in a systems medicine context. DZNE is also part of several national initiatives to standardize and provide compute resources to biologist. Here, the successful candidate will get the possibility to collaborate with major players in the field.
Your profile:

  •  PhD or equivalent in bioinformatics, computer science or a related field,
  •  Experience in computational biology, bioinformatics or biomathematics is a plus,
  •  Experience in the analysis of Next-Generation Sequencing data e.g. single cell RNA-Seq, bulk RNA-Seq and ATAC/ChIP-Seq,
  •  Strong background in biology, preferable immunology.Solid experience in R and in object-oriented software development, ideally with C++ and python,
  •  Experience in parallel computing and in-memory approaches is of advantage,
  •  Enthusiasm to work in a thriving academic research environment,
  •  An interest to work in an international environment,
  •  A collaborative attitude and the ability to work independently as well as in a team,
  •  Excellent verbal and written communication skills in English.

We offer:

  • a diverse and demanding job with one of the largest employers in the region
  • Participation in a challenging research project
  • State of the art technologies to tackle important scientific and medical questions
  • A thriving interdisciplinary research environment at the University of Bonn and the DZNE
  • Fully established bioinformatics department
  • Modular High Performance Computing Infrastructure with Memory-Driven Computing resources
  • Close collaboration with industry partners and early access to novel developments
  • Employment, payment and social benefits are determined by the Public Sector Collective Agreement (Tarifvertrag für den öffentlichen Dienst (TVöD Bund)
  • company pension scheme (VBL)
  • numerous offers of university sports
  • very good transport connections or the possibility to purchase a VRS major customer ticket or to use inexpensive parking facilities
  • a possibility to use the day care center
  • The position is initially limited to three years
  • salary according to salary group 13 TV-L

The University of Bonn is committed to diversity and equal opportunities. It is certified as a family-friendly university. Its aim is to increase the proportion of women in areas where women are under-represented and to particularly promote their careers. It therefore urges women with relevant qualifications to apply. Applications are treated in accordance with the Land Equality Act. The application of suitable people with proven severe disabilities and persons of equivalent status is particularly welcome.
If you are interested in this position, please send your applications (in English) including a CV, a brief statement of research experiences and interests, a list of publications (if applicable) and two references in a single PDF file by e-mail to office.immunogenomics@uni-bonn.de with the application code 12.21.331. by April 30,2021. Please address any questions regarding the position described to Dr. Thomas Ulas at the same address.

We are looking to fill this position as soon as possible.