gesamte Publikationen

Urwyler, O., Izadifar, A., Vandenbogaerde, S., Sachse, S., Misbaer, A., & Schmucker, D. (2019). Branch-restricted localization of phosphatase Prl-1 specifies axonal synaptogenesis domains. Science (New York, N.Y.), 364(6439), eaau9952. doi.org/10.1126/science.aau9952

Sachse, S. M., Lievens, S., Ribeiro, L. F., Dascenco, D., Masschaele, D., Horré, K., Misbaer, A., Vanderroost, N., De Smet, A. S., Salta, E., Erfurth, M. L., Kise, Y., Nebel, S., Van Delm, W., Plaisance, S., Tavernier, J., De Strooper, B., De Wit, J., & Schmucker, D. (2019). Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation. The EMBO journal, 38(6), e99669. doi.org/10.15252/embj.201899669

Koch, M., Nicolas, M., Zschaetzsch, M., de Geest, N., Claeys, A., Yan, J., Morgan, M. J., Erfurth, M. L., Holt, M., Schmucker, D., & Hassan, B. A. (2018). A Fat-Facets-Dscam1-JNK Pathway Enhances Axonal Growth in Development and after Injury. Frontiers in cellular neuroscience, 11, 416. doi.org/10.3389/fncel.2017.00416

Schmucker D. (2017). ABL to Integrate Opposing Cellular Growth Signals. Developmental cell, 42(2), 108–109. doi.org/10.1016/j.devcel.2017.07.006

Oliva, C., Soldano, A., Mora, N., De Geest, N., Claeys, A., Erfurth, M. L., Sierralta, J., Ramaekers, A., Dascenco, D., Ejsmont, R. K., Schmucker, D., Sanchez-Soriano, N., & Hassan, B. A. (2016). Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex. Developmental cell, 39(2), 267–278. doi.org/10.1016/j.devcel.2016.09.028

Etlioglu, H. E., Sun, W., Huang, Z., Chen, W., & Schmucker, D. (2016). Characterization of a Single Genomic Locus Encoding the Clustered Protocadherin Receptor Diversity in Xenopus tropicalis. G3 (Bethesda, Md.), 6(8), 2309–2318. doi.org/10.1534/g3.116.027995

Dascenco, D., Erfurth, M. L., Izadifar, A., Song, M., Sachse, S., Bortnick, R., Urwyler, O., Petrovic, M., Ayaz, D., He, H., Kise, Y., Thomas, F., Kidd, T., & Schmucker, D. (2015). Slit and Receptor Tyrosine Phosphatase 69D Confer Spatial Specificity to Axon Branching via Dscam1. Cell, 162(5), 1140–1154. doi.org/10.1016/j.cell.2015.08.003

Petrovic, M., & Schmucker, D. (2015). Axonal wiring in neural development: Target-independent mechanisms help to establish precision and complexity. BioEssays : news and reviews in molecular, cellular and developmental biology, 37(9), 996–1004. doi.org/10.1002/bies.201400222

Urwyler, O., Izadifar, A., Dascenco, D., Petrovic, M., He, H., Ayaz, D., Kremer, A., Lippens, S., Baatsen, P., Guérin, C. J., & Schmucker, D. (2015). Investigating CNS synaptogenesis at single-synapse resolution by combining reverse genetics with correlative light and electron microscopy. Development (Cambridge, England), 142(2), 394–405. doi.org/10.1242/dev.115071

Armitage, S. A., Sun, W., You, X., Kurtz, J., Schmucker, D., & Chen, W. (2014). Quantitative profiling of Drosophila melanogaster Dscam1 isoforms reveals no changes in splicing after bacterial exposure. PloS one, 9(10), e108660. doi.org/10.1371/journal.pone.0108660

He, H., Kise, Y., Izadifar, A., Urwyler, O., Ayaz, D., Parthasarthy, A., Yan, B., Erfurth, M. L., Dascenco, D., & Schmucker, D. (2014). Cell-intrinsic requirement of Dscam1 isoform diversity for axon collateral formation. Science (New York, N.Y.), 344(6188), 1182–1186. doi.org/10.1126/science.1251852

Kise, Y., & Schmucker, D. (2013). Role of self-avoidance in neuronal wiring. Current opinion in neurobiology, 23(6), 983–989. doi.org/10.1016/j.conb.2013.09.011

Sun, W., You, X., Gogol-Döring, A., He, H., Kise, Y., Sohn, M., Chen, T., Klebes, A., Schmucker, D., & Chen, W. (2013). Ultra-deep profiling of alternatively spliced Drosophila Dscam isoforms by circularization-assisted multi-segment sequencing. The EMBO journal, 32(14), 2029–2038. doi.org/10.1038/emboj.2013.144

Langen, M., Koch, M., Yan, J., De Geest, N., Erfurth, M. L., Pfeiffer, B. D., Schmucker, D., Moreau, Y., & Hassan, B. A. (2013). Mutual inhibition among postmitotic neurons regulates robustness of brain wiring in Drosophila. eLife, 2, e00337. doi.org/10.7554/eLife.00337

Schmucker, D., & Hassan, B. A. (2012). Hamlet Notches fate. Nature neuroscience, 15(2), 174–176. doi.org/10.1038/nn.3029

Meissirel, C., Ruiz de Almodovar, C., Knevels, E., Coulon, C., Chounlamountri, N., Segura, I., de Rossi, P., Vinckier, S., Anthonis, K., Deléglise, B., de Mol, M., Ali, C., Dassonville, K., Loyens, E., Honnorat, J., Michotte, Y., Rogemond, V., Smolders, I., Voets, T., Vivien, D., Schmucker, D., … Carmeliet, P. (2011). VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation. Proceedings of the National Academy of Sciences of the United States of America, 108(33), 13782–13787. doi.org/10.1073/pnas.1100341108

Chen, B. E., Kondo, M., Garnier, A., Watson, F. L., Püettmann-Holgado, R., Lamar, D. R., & Schmucker, D. (2006). The molecular diversity of Dscam is functionally required for neuronal wiring specificity in Drosophila. Cell, 125(3), 607–620. doi.org/10.1016/j.cell.2006.03.034

Collins, J., Schmucker, D., Manoharan, V. (2009). Probing the reversibility of the Dscam Dimer with Light Scattering and Colloids.

Schmucker, D., & Chen, B. (2009). Dscam and DSCAM: complex genes in simple animals, complex animals yet simple genes. Genes & development, 23(2), 147–156. doi.org/10.1101/gad.1752909

Wang, J.-H., Chen, Q., Meijers, R., Schmucker, D., Liu, J., Zhang, H. (2008). Decoding homophilic recognition specificity of Dscam, a neuronal receptor with thousands isoforms. Acta Crystallographica Section A Foundations of Crystallography. 64. C89-C89. doi.org/10.1107/S0108767308097134

Collins, J., Arkus, N., Meng, G., Brenner, M., Schmucker, D., Manoharan, V. (2008). Complexity from Specificity: Light Scattering and Colloidal Studies of Dscam Self-Association.

Schmucker D. (2007). Molecular diversity of Dscam: recognition of molecular identity in neuronal wiring. Nature reviews. Neuroscience, 8(12), 915–920. doi.org/10.1038/nrn2256

Meijers, R., Puettmann-Holgado, R., Skiniotis, G., Liu, J. H., Walz, T., Wang, J. H., & Schmucker, D. (2007). Structural basis of Dscam isoform specificity. Nature, 449(7161), 487–491. doi.org/10.1038/nature06147

Hughes, M. E., Bortnick, R., Tsubouchi, A., Bäumer, P., Kondo, M., Uemura, T., & Schmucker, D. (2007). Homophilic Dscam interactions control complex dendrite morphogenesis. Neuron, 54(3), 417–427. doi.org/10.1016/j.neuron.2007.04.013

Kondo, M., Melcher, C., Erfurth, M.-L., Schmucker, D. (2006). Function and molecular diversity of the hypervariable receptor Dscam. Journal of Neurogenetics. 20. 148-148.

Chen, B. E., Kondo, M., Garnier, A., Watson, F. L., Püettmann-Holgado, R., Lamar, D. R., & Schmucker, D. (2006). The molecular diversity of Dscam is functionally required for neuronal wiring specificity in Drosophila. Cell, 125(3), 607–620. doi.org/10.1016/j.cell.2006.03.034

Watson, F. L., Püttmann-Holgado, R., Thomas, F., Lamar, D. L., Hughes, M., Kondo, M., Rebel, V. I., & Schmucker, D. (2005). Extensive diversity of Ig-superfamily proteins in the immune system of insects. Science (New York, N.Y.), 309(5742), 1874–1878. doi.org/10.1126/science.1116887

Schmucker, D., & Flanagan, J. G. (2004). Generation of recognition diversity in the nervous system. Neuron, 44(2), 219–222. doi.org/10.1016/j.neuron.2004.10.004

Schmucker D. (2003). Downstream of guidance receptors: entering the baroque period of axon guidance signaling. Neuron, 40(1), 4–6. doi.org/10.1016/s0896-6273(03)00603-2

Schmucker, D., & Zipursky, S. L. (2001). Signaling downstream of Eph receptors and ephrin ligands. Cell, 105(6), 701–704. doi.org/10.1016/s0092-8674(01)00391-9

Schmucker, D., Clemens, J. C., Shu, H., Worby, C. A., Xiao, J., Muda, M., Dixon, J. E., & Zipursky, S. L. (2000). Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell, 101(6), 671–684. doi.org/10.1016/s0092-8674(00)80878-8

Schmucker, D., Vorbrüggen, G., Yeghiayan, P., Fan, H. Q., Jäckle, H., & Gaul, U. (2000). The Drosophila gene abstrakt, required for visual system development, encodes a putative RNA helicase of the DEAD box protein family. Mechanisms of development, 91(1-2), 189–196. doi.org/10.1016/s0925-4773(99)00298-1

Sheng, G., Thouvenot, E., Schmucker, D., Wilson, D. S., & Desplan, C. (1997). Direct regulation of rhodopsin 1 by Pax-6/eyeless in Drosophila: evidence for a conserved function in photoreceptors. Genes & development, 11(9), 1122–1131. doi.org/10.1101/gad.11.9.1122

Schmucker, D., Jäckle, H., & Gaul, U. (1997). Genetic analysis of the larval optic nerve projection in Drosophila. Development (Cambridge, England), 124(5), 937–948.

Schmucker, D., Su, A. L., Beermann, A., Jäckle, H., & Jay, D. G. (1994). Chromophore-assisted laser inactivation of patched protein switches cell fate in the larval visual system of Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 91(7), 2664–2668. doi.org/10.1073/pnas.91.7.2664

Schmucker, D., Taubert, H., & Jäckle, H. (1992). Formation of the Drosophila larval photoreceptor organ and its neuronal differentiation require continuous Krüppel gene activity. Neuron, 9(6), 1025–1039. doi.org/10.1016/0896-6273(92)90063-j