ausgewählte Publikationen

Izadifar A, Courchet J, Virga DM, Verreet T, Hamilton S, Ayaz D, Misbaer A, Vandenbogaerde S, Monteiro L, Petrovic M, Sachse S, Yan B, Erfurth ML, Dascenco D, Kise Y, Yan J, Edwards-Faret G, Lewis T, Polleux F, Schmucker D.
Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.
Neuron. 2021; 109(18). doi.org/10.15252/embj.201899669.

Sachse SM, Lievens S, Ribeiro LF, Dascenco D, Masschaele D, Horré K, Misbaer A, Vanderroost N, De Smet AS, Salta E, Erfurth ML, Kise Y, Nebel S, Van Delm W, Plaisance S, Tavernier J, De Strooper B, De Wit J, Schmucker D.
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation.
EMBO J. 2019; 38(6). pii: e99669. doi.org/10.15252/embj.201899669.Sachse SM, Lievens S, Ribeiro LF, Dascenco D, Masschaele D, Horré K, Misbaer A, Vanderroost N, De Smet AS, Salta E, Erfurth ML, Kise Y, Nebel S, Van Delm W, Plaisance S, Tavernier J, De Strooper B, De Wit J, Schmucker D.

Urwyler O, Izadifar A, Vandenbogaerde S, Sachse S, Misbaer A, Schmucker D.
Branch-restricted localization of phosphatase Prl-1 specifies axonal synaptogenesis domains.
Science. 2019; 364, eaau9952 (2019). doi.org/10.1126/science.aau9952

Etlioglu H. E., Sun W., Zengjin Huang Z., Chen W., Schmucker, D.
Characterization of a single genomic locus encoding the clustered protocadherin receptor diversity in Xenopus tropicalis.
G3: Genes, Genomes, Genetics 2016; 6(8):2309-18. doi.org/10.1534/g3.116.027995

Dascenco D, M-L., Erfurth, A., Izadifar,  M. Song, S., Sachse, R., Bortnick, O., Urwyler, M., Petrovic, D.; Ayaz, H., He, Y. Kise, F., Thomas, T., Kidd; D., Schmucker.
Slit and Receptor Tyrosine Phosphatase 69D Confer Spatial Specificity to Axon Branching via Dscam1.
Cell 2015; 162, 1140-54. doi.org/10.1016/j.cell.2015.08.003

Urwyler O, A. Izadifar, D. Dascenco, M. Petrovic, H. He, D. Ayaz, A. Kremer, S. Lippens, P. Baatsen, C. J. Guérin, D. Schmucker.
Investigating CNS Synaptogenesis at Single Synapse Resolution: Combining Reverse Genetics and Correlative Light and Electron Microscopy.
Development 2015; 142 (2) 394-405. doi.org/10.1242/dev.115071

H. He, Y. Kise, A. Izadifar, O. Urwyler, D. Ayaz, A. Parthasarthy, B. Yan, M.-L. Erfurth, D. Dascenco, and Schmucker, D.
Cell-intrinsic requirement of Dscam isoform diversity.
Science 2014; 344: 1182-1186. doi.org/10.1126/science.1251852

Meijers, R, Püttmann-Holgado R, Skiniotis G, Liu J-H, Walz, T, Wang J-H, Schmucker D.
Structural Basis of Dscam Isoform specificity.
Nature 2007; 449: 487-91. doi.org/10.1038/nature06147

Hughes E M, Bortnik R. Tsubouchi, A. Bäumer P, Kondo M, Uemura, T. Schmucker D.
Homotypic Dscam-Dscam interactions control complex dendrite morphogenesis.
Neuron 2007; 54, 417-427. doi.org/10.1016/j.neuron.2007.04.013

Chen BE, Kondo M, Garnier A, Watson FL, Püttmann-Holgado R, Lamar DR and Schmucker D.
The molecular diversity of Dscam is functionally required for neuronal wiring specificity in Drosophila.
Cell. 2006; 125: 607-20. doi.org/10.1016/j.cell.2006.03.034

Watson FL, Püttmann-Holgado R, Thomas F, Lamar DL, Hughes M, Kondo M, Rebel V. and Schmucker D. Extensive diversity of Ig-superfamily proteins in the immune system of insects.
Science. 2005; 309: 1874-8. doi.org/10.1126/science.1116887

Schmucker D, Clemens JC, Shu H, Worby CA, Xiao J, Muda M, Dixon JE and Zipursky SL.
Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity.
Cell. 2000; 101: 671-84. doi.org/10.1016/s0092-8674(00)80878-8